Antibacterial activity and acute toxicity study of standardized aqueous extract of Randia monantha Benth fruit

The fruit of Randia monantha is traditionally and empirically used in the preparation a beverage as antivenom for treatment various diseases, but to date there little scientific evidence regarding its antimicrobiological properties toxicity. objective this study was evaluar effect administration aqueous extract pulp on acute toxicity male Wistar rats evaluate antimicrobial activity at different concentrations against pathogenic bacteria. results oral revealed no deaths doses up 5000 mg / kg body weight. experimental animals showed significant changes weight behavior parameters evaluated with respect control treatment. Rats did not show hematological parameters, dosis mg/kg exhibited appearance yellow spots kidney. test These suggest that can be some degree safety by should taken high doses.